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Pelvic inflammatory disease is most frequently caused by bacteria that are transmitted through sexual contact and other bodily secretions. Bacteria that cause gonorrhea and chlamydia cause more than half of cases. Many studies suggest that a number of patients with PID and other sexually transmitted diseases are often infected with two or more infectious agents, and commonly these are Chlamydia trachomatis and Neisseria gonorrhoeae. Other organisms can also cause PID but are much less common.